Effect of Alerts for Drug Dosage Adjustment in Inpatients with Renal Insufficiency

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Research Paper: Effect of Alerts for Drug Dosage Adjustment in Inpatients with Renal Insufficiency

OBJECTIVES Medication errors constitute a major problem in all hospitals. Between 20% and 46% of prescriptions requiring dosage adjustments based on renal function are inappropriate. This study aimed to determine whether implementing alerts at the time of ordering medication integrated into the computerized physician order entry decreases the proportion of inappropriate prescriptions based on t...

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The Rate of Antibiotic Dosage Adjustment in Renal Dysfunction

The purpose of this study was to determine the number of prescribed antibiotics being appropriately adjusted and to assess antibiotics with the highest incorrect dosing based on the patient’s renal function according to distinguished guidelines. The study was conducted at a 446-bed university hospital. One hundred and fifty patients admitted through different wards of the hospital were included...

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Dose Adjustment of Polymyxins for Renal Insufficiency

In a recent article, Garonzik et al. (4) importantly advanced our knowledge of the pharmacokinetics (PK) of colistin methanesulfonate (CMS) and the active drug that it forms, colistin. In their elegant population PK study of critically ill patients, the authors demonstrated that creatinine clearance (CLCR) significantly affects the total body clearance of CMS and colistin (4). It is important t...

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In a recent article, Garonzik et al. (4) importantly advanced our knowledge of the pharmacokinetics (PK) of colistin methanesulfonate (CMS) and the active drug that it forms, colistin. In their elegant population PK study of critically ill patients, the authors demonstrated that creatinine clearance (CLCR) significantly affects the total body clearance of CMS and colistin (4). It is important t...

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ژورنال

عنوان ژورنال: Journal of the American Medical Informatics Association

سال: 2009

ISSN: 1067-5027,1527-974X

DOI: 10.1197/jamia.m2805